The game tips at 6:05 p.m. ET and will be televised on CBS.
Most folks would say that this one is Louisville's to lose. They're clearly the most talented team in the tournament and, coupled with the karma of the Kevin Ware situation, they're basically Team Destiny right now.
But you know who hates narratives? Wichita State, who by all accounts should not be here right now. It sounds crazy to think the Shockers could win this game, but then again, that's their name.
Leave your pre-, in- and post-game comments below as we prepare to say G'ORANGE!